2fkl: Difference between revisions

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{{Seed}}
[[Image:2fkl.png|left|200px]]
[[Image:2fkl.png|left|200px]]


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===Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain (Residues 126- 189 of APP)===
===Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain (Residues 126- 189 of APP)===


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{{ABSTRACT_PUBMED_17239395}}
{{ABSTRACT_PUBMED_17239395}}


==Disease==
==About this Structure==
Known disease associated with this structure: Alzheimer disease-1, APP-related OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]], Amyloidosis, cerebroarterial, Dutch type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]], Amyloidosis, cerebroarterial, Iowa type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]]
[[2fkl]] is a 2 chain structure of [[Amyloid precursor protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKL OCA].


==About this Structure==
==See Also==
2FKL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKL OCA].
*[[Amyloid precursor protein|Amyloid precursor protein]]


==Reference==
==Reference==
<ref group="xtra">PMID:17239395</ref><references group="xtra"/>
<ref group="xtra">PMID:017239395</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kong, G K.W.]]
[[Category: Kong, G K.W.]]
[[Category: Parker, M W.]]
[[Category: Parker, M W.]]
[[Category: Alpha-beta two-layered sandwich]]
[[Category: Alpha-beta two-layered sandwich]]
 
[[Category: Metal binding protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:34:43 2009''

Revision as of 01:55, 27 July 2012

File:2fkl.png


Drag the structure with the mouse to rotate
2fkl, resolution 2.50Å (default scene)
Gene: APP (Homo sapiens)
Related: 1owt, 2fjz, 2fk1, 2fk2, 2fk3
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain (Residues 126- 189 of APP)

Template:ABSTRACT PUBMED 17239395

About this Structure

2fkl is a 2 chain structure of Amyloid precursor protein with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Kong GK, Adams JJ, Harris HH, Boas JF, Curtain CC, Galatis D, Masters CL, Barnham KJ, McKinstry WJ, Cappai R, Parker MW. Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions. J Mol Biol. 2007 Mar 16;367(1):148-61. Epub 2006 Dec 21. PMID:17239395 doi:10.1016/j.jmb.2006.12.041

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