2aqb: Difference between revisions
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[[Image:2aqb.png|left|200px]] | [[Image:2aqb.png|left|200px]] | ||
{{STRUCTURE_2aqb| PDB=2aqb | SCENE= }} | {{STRUCTURE_2aqb| PDB=2aqb | SCENE= }} | ||
===Structure-activity relationships at the 5-position of thiolactomycin: an intact 5(R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherchia coli=== | ===Structure-activity relationships at the 5-position of thiolactomycin: an intact 5(R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherchia coli=== | ||
{{ABSTRACT_PUBMED_16392800}} | {{ABSTRACT_PUBMED_16392800}} | ||
==About this Structure== | ==About this Structure== | ||
[[2aqb]] is a 4 chain structure of [[Acyl carrier protein synthase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQB OCA]. | |||
==See Also== | |||
*[[Acyl carrier protein synthase|Acyl carrier protein synthase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016392800</ref><references group="xtra"/> | ||
[[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | [[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
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[[Category: Zhang, Y M.]] | [[Category: Zhang, Y M.]] | ||
[[Category: Fabb-ligand active-site complex]] | [[Category: Fabb-ligand active-site complex]] | ||
[[Category: Transferase]] | |||
Revision as of 02:03, 27 July 2012
Structure-activity relationships at the 5-position of thiolactomycin: an intact 5(R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherchia coli
Template:ABSTRACT PUBMED 16392800
About this Structure
2aqb is a 4 chain structure of Acyl carrier protein synthase with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Kim P, Zhang YM, Shenoy G, Nguyen QA, Boshoff HI, Manjunatha UH, Goodwin MB, Lonsdale J, Price AC, Miller DJ, Duncan K, White SW, Rock CO, Barry CE 3rd, Dowd CS. Structure-activity relationships at the 5-position of thiolactomycin: an intact (5R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherichia coli. J Med Chem. 2006 Jan 12;49(1):159-71. PMID:16392800 doi:https://dx.doi.org/10.1021/jm050825p
