3h59: Difference between revisions
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[[Image:3h59.png|left|200px]] | [[Image:3h59.png|left|200px]] | ||
{{STRUCTURE_3h59| PDB=3h59 | SCENE= }} | {{STRUCTURE_3h59| PDB=3h59 | SCENE= }} | ||
===Hepatitis C virus polymerase NS5B with thiazine inhibitor 2=== | ===Hepatitis C virus polymerase NS5B with thiazine inhibitor 2=== | ||
{{ABSTRACT_PUBMED_19700319}} | {{ABSTRACT_PUBMED_19700319}} | ||
==About this Structure== | ==About this Structure== | ||
[[3h59]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H59 OCA]. | |||
==See Also== | |||
*[[RNA polymerase|RNA polymerase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019700319</ref><references group="xtra"/> | ||
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Ghate, M.]] | [[Category: Ghate, M.]] | ||
[[Category: Harris, S F.]] | [[Category: Harris, S F.]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Capsid protein]] | [[Category: Capsid protein]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
[[Category: Endoplasmic reticulum]] | [[Category: Endoplasmic reticulum]] | ||
| Line 72: | Line 61: | ||
[[Category: Transferase rna-dependent rna polymerase]] | [[Category: Transferase rna-dependent rna polymerase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
Revision as of 02:50, 27 July 2012
Hepatitis C virus polymerase NS5B with thiazine inhibitor 2
Template:ABSTRACT PUBMED 19700319
About this Structure
3h59 is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- de Vicente J, Hendricks RT, Smith DB, Fell JB, Fischer J, Spencer SR, Stengel PJ, Mohr P, Robinson JE, Blake JF, Hilgenkamp RK, Yee C, Zhao J, Elworthy TR, Tracy J, Chin E, Li J, Lui A, Wang B, Oshiro C, Harris SF, Ghate M, Leveque VJ, Najera I, Le Pogam S, Rajyaguru S, Ao-Ieong G, Alexandrova L, Fitch B, Brandl M, Masjedizadeh M, Wu SY, de Keczer S, Voronin T. Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5648-51. Epub 2009 Aug 8. PMID:19700319 doi:10.1016/j.bmcl.2009.08.023
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Hepatitis c virus
- RNA-directed RNA polymerase
- Ghate, M.
- Harris, S F.
- Apoptosis
- Atp-binding
- Capsid protein
- Cell membrane
- Disulfide bond
- Endoplasmic reticulum
- Envelope protein
- Fusion protein
- Glycoprotein
- Hcv
- Helicase
- Hepatitis
- Host-virus interaction
- Hydrolase
- Interferon antiviral system evasion
- Lipid droplet
- Lipoprotein
- Membrane
- Metal-binding
- Mitochondrion
- Multifunctional enzyme
- Ns5b
- Nucleotide-binding
- Nucleotidyltransferase
- Nucleus
- Oncogene
- Palmitate
- Phosphoprotein
- Protease
- Ribonucleoprotein
- Rna replication
- Rna-binding
- Rna-directed rna polymerase
- Secreted
- Serine protease
- Sh3-binding
- Thiol protease
- Transcription
- Transcription regulation
- Transferase
- Transferase rna-dependent rna polymerase
- Transmembrane
- Viral nucleoprotein
- Virion
