8est: Difference between revisions

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Revision as of 03:05, 27 July 2012

File:8est.png

Template:STRUCTURE 8est

REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN

Template:ABSTRACT PUBMED 2337582

About this Structure

8est is a 1 chain structure of Elastase with sequence from Sus scrofa. Full crystallographic information is available from OCA.

See Also

Reference

  1. Powers JC, Oleksyszyn J, Narasimhan SL, Kam CM. Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin. Biochemistry. 1990 Mar 27;29(12):3108-18. PMID:2337582
  2. Peisach E, Casebier D, Gallion SL, Furth P, Petsko GA, Hogan JC Jr, Ringe D. Interaction of a peptidomimetic aminimide inhibitor with elastase. Science. 1995 Jul 7;269(5220):66-9. PMID:7604279

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