3hpt: Difference between revisions
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[[Image:3hpt.png|left|200px]] | |||
[[Image:3hpt. | |||
{{STRUCTURE_3hpt| PDB=3hpt | SCENE= }} | {{STRUCTURE_3hpt| PDB=3hpt | SCENE= }} | ||
===Crystal structure of human FxA in complex with (S)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine=== | ===Crystal structure of human FxA in complex with (S)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine=== | ||
{{ABSTRACT_PUBMED_19541481}} | {{ABSTRACT_PUBMED_19541481}} | ||
==About this Structure== | ==About this Structure== | ||
[[3hpt]] is a 4 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HPT OCA]. | |||
==See Also== | |||
*[[Factor Xa|Factor Xa]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019541481</ref><references group="xtra"/> | ||
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Blood coagulation factor]] | [[Category: Blood coagulation factor]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydroxylation]] | [[Category: Hydroxylation]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 04:33, 27 July 2012
Crystal structure of human FxA in complex with (S)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine
Template:ABSTRACT PUBMED 19541481
About this Structure
3hpt is a 4 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Shi Y, Zhang J, Shi M, O'Connor SP, Bisaha SN, Li C, Sitkoff D, Pudzianowski AT, Chong S, Klei HE, Kish K, Yanchunas J Jr, Liu EC, Hartl KS, Seiler SM, Steinbacher TE, Schumacher WA, Atwal KS, Stein PD. Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4034-41. Epub 2009 Jun 13. PMID:19541481 doi:10.1016/j.bmcl.2009.06.014
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Ghosh, K.
- Kish, K.
- Klei, H E.
- Rushith, A.
- Blood clotting
- Blood coagulation
- Blood coagulation factor
- Cleavage on pair of basic residue
- Disulfide bond
- Egf-like domain
- Epidermal growth factor like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Protease
- Secreted
- Serine protease
- Zymogen