3k5f: Difference between revisions

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{{Seed}}
[[Image:3k5f.png|left|200px]]
[[Image:3k5f.jpg|left|200px]]


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{{STRUCTURE_3k5f|  PDB=3k5f  |  SCENE=  }}  
{{STRUCTURE_3k5f|  PDB=3k5f  |  SCENE=  }}  


===Human BACE-1 COMPLEX WITH AYH011===
===Human BACE-1 COMPLEX WITH AYH011===


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{{ABSTRACT_PUBMED_20172717}}
{{ABSTRACT_PUBMED_20172717}}


==About this Structure==
==About this Structure==
3K5F is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K5F OCA].  
[[3k5f]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K5F OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20172717</ref><references group="xtra"/>
<ref group="xtra">PMID:020172717</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Rondeau, J M.]]
[[Category: Rondeau, J M.]]
[[Category: Alternative splicing]]
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
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[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Golgi apparatus]]
[[Category: Golgi apparatus]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Structure-based design]]
[[Category: Structure-based design]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May  5 12:02:31 2010''

Revision as of 05:18, 27 July 2012

File:3k5f.png

Template:STRUCTURE 3k5f

Human BACE-1 COMPLEX WITH AYH011

Template:ABSTRACT PUBMED 20172717

About this Structure

3k5f is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Hanessian S, Shao Z, Betschart C, Rondeau JM, Neumann U, Tintelnot-Blomley M. Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1924-7. Epub 2010 Feb 2. PMID:20172717 doi:10.1016/j.bmcl.2010.01.139

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