3kli: Difference between revisions

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[[Image:3kli.png|left|200px]]
[[Image:3kli.png|left|200px]]


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{{STRUCTURE_3kli|  PDB=3kli  |  SCENE=  }}  
{{STRUCTURE_3kli|  PDB=3kli  |  SCENE=  }}  


===Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase===
===Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase===


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{{ABSTRACT_PUBMED_20852643}}
{{ABSTRACT_PUBMED_20852643}}


==About this Structure==
==About this Structure==
[[3kli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLI OCA].  
[[3kli]] is a 2 chain structure of [[AZT-resistant HIV-1 reverse transcriptase]] and [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLI OCA].  
 
==See Also==
*[[AZT-resistant HIV-1 reverse transcriptase|AZT-resistant HIV-1 reverse transcriptase]]
*[[Reverse transcriptase|Reverse transcriptase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20852643</ref><references group="xtra"/>
<ref group="xtra">PMID:020852643</ref><references group="xtra"/>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Arnold, E.]]
[[Category: Arnold, E.]]
[[Category: Sarafianos, S G.]]
[[Category: Sarafianos, S G.]]
[[Category: Tu, X.]]
[[Category: Tu, X.]]
[[Category: Aid]]
[[Category: Azt]]
[[Category: Azt resistance]]
[[Category: Azt resistance mechanism]]
[[Category: Azt resistance mutation]]
[[Category: Dna polymerase]]
[[Category: Dna recombination]]
[[Category: Hetero dimer]]
[[Category: Hiv]]
[[Category: Multifunctional enzyme]]
[[Category: Nrti]]
[[Category: Nucleoside inhibitor]]
[[Category: P51/p66]]
[[Category: Reverse transcriptase]]
[[Category: Rna-directed dna polymerase]]
[[Category: Transferase]]

Revision as of 05:25, 27 July 2012

File:3kli.png


Drag the structure with the mouse to rotate
3kli, resolution 2.65Å (default scene)
Gene: gag-pol (Human immunodeficiency virus 1)
Related: 3kle, 3klf, 3klg, 3klh


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase

Template:ABSTRACT PUBMED 20852643

About this Structure

3kli is a 2 chain structure of AZT-resistant HIV-1 reverse transcriptase and Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908

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