2rf2: Difference between revisions

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[[Image:2rf2.png|left|200px]]
[[Image:2rf2.png|left|200px]]


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{{STRUCTURE_2rf2|  PDB=2rf2  |  SCENE=  }}  
{{STRUCTURE_2rf2|  PDB=2rf2  |  SCENE=  }}  


===HIV reverse transcriptase in complex with inhibitor 7e (NNRTI)===
===HIV reverse transcriptase in complex with inhibitor 7e (NNRTI)===


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{{ABSTRACT_PUBMED_18083561}}
{{ABSTRACT_PUBMED_18083561}}


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==See Also==
==See Also==
*[[Reverse transcriptase]]
*[[Reverse transcriptase|Reverse transcriptase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18083561</ref><references group="xtra"/>
<ref group="xtra">PMID:018083561</ref><references group="xtra"/>
[[Category: Hiv-1 m:b_hxb2r]]
[[Category: Hiv-1 m:b_hxb2r]]
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
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[[Category: Capsid maturation]]
[[Category: Capsid maturation]]
[[Category: Core protein]]
[[Category: Core protein]]
[[Category: Cytoplasm]]
[[Category: Dna integration]]
[[Category: Dna integration]]
[[Category: Dna recombination]]
[[Category: Dna recombination]]
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[[Category: Rna-binding]]
[[Category: Rna-binding]]
[[Category: Rna-directed dna polymerase]]
[[Category: Rna-directed dna polymerase]]
[[Category: Transferase]]
[[Category: Viral nucleoprotein]]
[[Category: Viral nucleoprotein]]
[[Category: Virion]]
[[Category: Virion]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]

Revision as of 05:37, 27 July 2012

File:2rf2.png

Template:STRUCTURE 2rf2

HIV reverse transcriptase in complex with inhibitor 7e (NNRTI)

Template:ABSTRACT PUBMED 18083561

About this Structure

2rf2 is a 2 chain structure of Reverse transcriptase with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

See Also

Reference

  1. Zhao Z, Wolkenberg SE, Sanderson PE, Lu M, Munshi V, Moyer G, Feng M, Carella AV, Ecto LT, Gabryelski LJ, Lai MT, Prasad SG, Yan Y, McGaughey GB, Miller MD, Lindsley CW, Hartman GD, Vacca JP, Williams TM. Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs). Bioorg Med Chem Lett. 2008 Jan 15;18(2):554-9. Epub 2007 Nov 28. PMID:18083561 doi:10.1016/j.bmcl.2007.11.085

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