3ens: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:
{{Seed}}
[[Image:3ens.png|left|200px]]
[[Image:3ens.jpg|left|200px]]


<!--
The line below this paragraph, containing "STRUCTURE_3ens", creates the "Structure Box" on the page.
You may change the PDB parameter (which sets the PDB file loaded into the applet)
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
or leave the SCENE parameter empty for the default display.
-->
{{STRUCTURE_3ens|  PDB=3ens  |  SCENE=  }}  
{{STRUCTURE_3ens|  PDB=3ens  |  SCENE=  }}  


===Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate===
===Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate===


<!--
The line below this paragraph, {{ABSTRACT_PUBMED_18998662}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 18998662 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_18998662}}
{{ABSTRACT_PUBMED_18998662}}


==About this Structure==
==About this Structure==
3ENS is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ENS OCA].  
[[3ens]] is a 4 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ENS OCA].  
 
==See Also==
*[[Factor Xa|Factor Xa]]


==Reference==
==Reference==
Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors., Shi Y, Sitkoff D, Zhang J, Klei HE, Kish K, Liu EC, Hartl KS, Seiler SM, Chang M, Huang C, Youssef S, Steinbacher TE, Schumacher WA, Grazier N, Pudzianowski A, Apedo A, Discenza L, Yanchunas J Jr, Stein PD, Atwal KS, J Med Chem. 2008 Nov 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18998662 18998662]
<ref group="xtra">PMID:018998662</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 29: Line 20:
[[Category: Blood clotting]]
[[Category: Blood clotting]]
[[Category: Blood coagulation factor]]
[[Category: Blood coagulation factor]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Egf-like domain]]
[[Category: Egf-like domain]]
Line 37: Line 27:
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Hydroxylation]]
[[Category: Polymorphism]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 10:33:40 2008''
Retrieved from "https://proteopedia.org/3ens"