3fh7: Difference between revisions

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{{Seed}}
[[Image:3fh7.png|left|200px]]
[[Image:3fh7.png|left|200px]]


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{{STRUCTURE_3fh7|  PDB=3fh7  |  SCENE=  }}  
{{STRUCTURE_3fh7|  PDB=3fh7  |  SCENE=  }}  


===Leukotriene A4 Hydrolase complexed with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate.===
===Leukotriene A4 Hydrolase complexed with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate.===


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{{ABSTRACT_PUBMED_19950900}}
{{ABSTRACT_PUBMED_19950900}}


==About this Structure==
==About this Structure==
3FH7 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FH7 OCA].  
[[3fh7]] is a 1 chain structure of [[Leukotriene A4 Hydrolase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FH7 OCA].  
 
==See Also==
*[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19950900</ref><references group="xtra"/>
<ref group="xtra">PMID:019950900</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Davies, D R.]]
[[Category: Davies, D R.]]
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[[Category: Protease]]
[[Category: Protease]]
[[Category: Structure based drug design]]
[[Category: Structure based drug design]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:14:16 2010''

Revision as of 07:34, 27 July 2012

File:3fh7.png

Template:STRUCTURE 3fh7

Leukotriene A4 Hydrolase complexed with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate.

Template:ABSTRACT PUBMED 19950900

About this Structure

3fh7 is a 1 chain structure of Leukotriene A4 Hydrolase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sandanayaka V, Mamat B, Mishra RK, Winger J, Krohn M, Zhou LM, Keyvan M, Enache L, Sullins D, Onua E, Zhang J, Halldorsdottir G, Sigthorsdottir H, Thorlaksdottir A, Sigthorsson G, Thorsteinnsdottir M, Davies DR, Stewart LJ, Zembower DE, Andresson T, Kiselyov AS, Singh J, Gurney ME. Discovery of 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic Acid (DG-051) as a Novel Leukotriene A4 Hydrolase Inhibitor of Leukotriene B4 Biosynthesis. J Med Chem. 2009 Dec 1. PMID:19950900 doi:10.1021/jm900838g

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