1xxd: Difference between revisions

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Revision as of 07:42, 27 July 2012

File:1xxd.png

Template:STRUCTURE 1xxd

Crystal Structure of the FXIa Catalytic Domain in Complex with mutated Ecotin

Template:ABSTRACT PUBMED 15545266

About this Structure

1xxd is a 4 chain structure of Ecotin and Factor XIa with sequence from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Jin L, Pandey P, Babine RE, Gorga JC, Seidl KJ, Gelfand E, Weaver DT, Abdel-Meguid SS, Strickler JE. Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions. J Biol Chem. 2005 Feb 11;280(6):4704-12. Epub 2004 Nov 15. PMID:15545266 doi:10.1074/jbc.M411309200
  2. Takamiya O, Machida S, Yamamoto M. Factor XI deficiency with a novel homozygous mutation Trp599Arg near the C-terminal region. Haematologica. 2005 Jul;90(7):999-1001. PMID:15996948

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