3hhm: Difference between revisions

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[[Image:3hhm.png|left|200px]]
[[Image:3hhm.png|left|200px]]


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{{STRUCTURE_3hhm|  PDB=3hhm  |  SCENE=  }}  
{{STRUCTURE_3hhm|  PDB=3hhm  |  SCENE=  }}  


===Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin===
===Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin===


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{{ABSTRACT_PUBMED_19805105}}


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==See Also==
==See Also==
*[[Phosphoinositide 3-Kinases]]
*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]
*[[The Structure of PI3K|The Structure of PI3K]]


==Reference==
==Reference==
<ref group="xtra">PMID:19805105</ref><references group="xtra"/>
<ref group="xtra">PMID:019805105</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Pi3kca]]
[[Category: Pi3kca]]
[[Category: Pik3r1]]
[[Category: Pik3r1]]
[[Category: Polymorphism]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transferase/oncoprotein complex]]
[[Category: Transferase-oncoprotein complex]]
[[Category: Wortmannin]]
[[Category: Wortmannin]]

Revision as of 07:56, 27 July 2012

File:3hhm.png

Template:STRUCTURE 3hhm

Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin

Template:ABSTRACT PUBMED 19805105

About this Structure

3hhm is a 2 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM. A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16996-7001. Epub 2009 Sep 23. PMID:19805105

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