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Revision as of 08:05, 27 July 2012

File:1nce.png

Template:STRUCTURE 1nce

Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717

Template:ABSTRACT PUBMED 12702803

About this Structure

1nce is a 2 chain structure of Thymidylate synthase with sequence from Escherichia coli, escherichia coli o157:h7. Full crystallographic information is available from OCA.

See Also

Reference

  1. Birdsall DL, Finer-Moore J, Stroud RM. The only active mutant of thymidylate synthase D169, a residue far from the site of methyl transfer, demonstrates the exquisite nature of enzyme specificity. Protein Eng. 2003 Mar;16(3):229-40. PMID:12702803

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