3igv: Difference between revisions

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{{Seed}}
[[Image:3igv.png|left|200px]]
[[Image:3igv.jpg|left|200px]]


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{{STRUCTURE_3igv|  PDB=3igv  |  SCENE=  }}  
{{STRUCTURE_3igv|  PDB=3igv  |  SCENE=  }}  


===Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor===
===Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor===


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{{ABSTRACT_PUBMED_19796938}}
{{ABSTRACT_PUBMED_19796938}}


==About this Structure==
==About this Structure==
3IGV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IGV OCA].  
[[3igv]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IGV OCA].  
 
==See Also==
*[[RNA polymerase|RNA polymerase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19796938</ref><references group="xtra"/>
<ref group="xtra">PMID:019796938</ref><references group="xtra"/>
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Viruses]]
[[Category: Viruses]]
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[[Category: Viral nucleoprotein]]
[[Category: Viral nucleoprotein]]
[[Category: Virion]]
[[Category: Virion]]
[[Category: Zinc]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  9 15:00:07 2009''

Revision as of 08:25, 27 July 2012

File:3igv.png

Template:STRUCTURE 3igv

Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor

Template:ABSTRACT PUBMED 19796938

About this Structure

3igv is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ellis DA, Blazel JK, Tran CV, Ruebsam F, Murphy DE, Li LS, Zhao J, Zhou Y, McGuire HM, Xiang AX, Webber SE, Zhao Q, Han Q, Kissinger CR, Lardy M, Gobbi A, Showalter RE, Shah AM, Tsan M, Patel RA, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6047-52. Epub 2009 Sep 17. PMID:19796938 doi:10.1016/j.bmcl.2009.09.051

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