2h48: Difference between revisions

Revision as of 08:55, 27 July 2012

2h48 is a 3 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Scheer JM, Romanowski MJ, Wells JA. A common allosteric site and mechanism in caspases. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7595-600. Epub 2006 May 8. PMID:16682620

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 [[Image:2h48.png|left|200px]]
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 ===Crystal structure of human caspase-1 (Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)===
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 {{ABSTRACT_PUBMED_16682620}}