1m7a: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:1m7a.png|left|200px]] | [[Image:1m7a.png|left|200px]] | ||
{{STRUCTURE_1m7a| PDB=1m7a | SCENE= }} | {{STRUCTURE_1m7a| PDB=1m7a | SCENE= }} | ||
===CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 7-[2-methoxy-1-(methoxymethyl)ethyl]-7H-pyrrolo[3,2-f] quinazoline-1,3-diamine (GW557)=== | ===CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 7-[2-methoxy-1-(methoxymethyl)ethyl]-7H-pyrrolo[3,2-f] quinazoline-1,3-diamine (GW557)=== | ||
{{ABSTRACT_PUBMED_9374515}} | {{ABSTRACT_PUBMED_9374515}} | ||
==About this Structure== | ==About this Structure== | ||
[[1m7a]] is a 2 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7A OCA]. | |||
==See Also== | |||
*[[Dihydrofolate reductase|Dihydrofolate reductase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:009374515</ref><references group="xtra"/> | ||
[[Category: Candida albicans]] | [[Category: Candida albicans]] | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
| Line 32: | Line 23: | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Reductase]] | [[Category: Reductase]] | ||
Revision as of 09:14, 27 July 2012
CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 7-[2-methoxy-1-(methoxymethyl)ethyl]-7H-pyrrolo[3,2-f] quinazoline-1,3-diamine (GW557)
Template:ABSTRACT PUBMED 9374515
About this Structure
1m7a is a 2 chain structure of Dihydrofolate reductase with sequence from Candida albicans. Full crystallographic information is available from OCA.
See Also
Reference
- Whitlow M, Howard AJ, Stewart D, Hardman KD, Kuyper LF, Baccanari DP, Fling ME, Tansik RL. X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex. J Biol Chem. 1997 Nov 28;272(48):30289-98. PMID:9374515