2is0: Difference between revisions
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[[Image:2is0.png|left|200px]] | [[Image:2is0.png|left|200px]] | ||
{{STRUCTURE_2is0| PDB=2is0 | SCENE= }} | {{STRUCTURE_2is0| PDB=2is0 | SCENE= }} | ||
===Crystal structure of human Beta-secretase complexed with inhibitor=== | ===Crystal structure of human Beta-secretase complexed with inhibitor=== | ||
{{ABSTRACT_PUBMED_17149856}} | {{ABSTRACT_PUBMED_17149856}} | ||
==About this Structure== | ==About this Structure== | ||
[[2is0]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IS0 OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017149856</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 09:40, 27 July 2012
Crystal structure of human Beta-secretase complexed with inhibitor
Template:ABSTRACT PUBMED 17149856
About this Structure
2is0 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Rajapakse HA, Nantermet PG, Selnick HG, Munshi S, McGaughey GB, Lindsley SR, Young MB, Lai MT, Espeseth AS, Shi XP, Colussi D, Pietrak B, Crouthamel MC, Tugusheva K, Huang Q, Xu M, Simon AJ, Kuo L, Hazuda DJ, Graham S, Vacca JP. Discovery of oxadiazoyl tertiary carbinamine inhibitors of beta-secretase (BACE-1). J Med Chem. 2006 Dec 14;49(25):7270-3. PMID:17149856 doi:10.1021/jm061046r
