1zgi: Difference between revisions

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{{Seed}}
[[Image:1zgi.png|left|200px]]
[[Image:1zgi.png|left|200px]]


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{{STRUCTURE_1zgi|  PDB=1zgi  |  SCENE=  }}  
{{STRUCTURE_1zgi|  PDB=1zgi  |  SCENE=  }}  


===thrombin in complex with an oxazolopyridine inhibitor 21===
===thrombin in complex with an oxazolopyridine inhibitor 21===


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{{ABSTRACT_PUBMED_16137886}}
{{ABSTRACT_PUBMED_16137886}}


==About this Structure==
==About this Structure==
1ZGI is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZGI OCA].  
[[1zgi]] is a 2 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZGI OCA].  
 
==See Also==
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:16137886</ref><references group="xtra"/>
<ref group="xtra">PMID:016137886</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
Line 40: Line 32:
[[Category: Williams, P D.]]
[[Category: Williams, P D.]]
[[Category: Yan, Y.]]
[[Category: Yan, Y.]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Thrombin inhibitor complex]]
[[Category: Thrombin inhibitor complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:40:13 2009''

Revision as of 09:53, 27 July 2012

File:1zgi.png

Template:STRUCTURE 1zgi

thrombin in complex with an oxazolopyridine inhibitor 21

Template:ABSTRACT PUBMED 16137886

About this Structure

1zgi is a 2 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Deng JZ, McMasters DR, Rabbat PM, Williams PD, Coburn CA, Yan Y, Kuo LC, Lewis SD, Lucas BJ, Krueger JA, Strulovici B, Vacca JP, Lyle TA, Burgey CS. Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4411-6. PMID:16137886 doi:https://dx.doi.org/10.1016/j.bmcl.2005.07.022

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