2hai: Difference between revisions
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[[Image:2hai.png|left|200px]] | [[Image:2hai.png|left|200px]] | ||
{{STRUCTURE_2hai| PDB=2hai | SCENE= }} | {{STRUCTURE_2hai| PDB=2hai | SCENE= }} | ||
===Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor.=== | ===Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor.=== | ||
{{ABSTRACT_PUBMED_16824756}} | {{ABSTRACT_PUBMED_16824756}} | ||
==About this Structure== | ==About this Structure== | ||
[[2hai]] is a 1 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAI OCA]. | |||
==See Also== | |||
*[[RNA polymerase|RNA polymerase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016824756</ref><references group="xtra"/> | ||
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
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[[Category: Love, R L.]] | [[Category: Love, R L.]] | ||
[[Category: Hcv rna polymerase]] | [[Category: Hcv rna polymerase]] | ||
[[Category: Transferase]] | |||
Revision as of 10:10, 27 July 2012
Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor.
Template:ABSTRACT PUBMED 16824756
About this Structure
2hai is a 1 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Li H, Tatlock J, Linton A, Gonzalez J, Borchardt A, Dragovich P, Jewell T, Prins T, Zhou R, Blazel J, Parge H, Love R, Hickey M, Doan C, Shi S, Duggal R, Lewis C, Fuhrman S. Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4834-8. Epub 2006 Jul 7. PMID:16824756 doi:10.1016/j.bmcl.2006.06.065
