2ec8: Difference between revisions

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{{Seed}}
[[Image:2ec8.png|left|200px]]
[[Image:2ec8.png|left|200px]]


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{{STRUCTURE_2ec8|  PDB=2ec8  |  SCENE=  }}  
{{STRUCTURE_2ec8|  PDB=2ec8  |  SCENE=  }}  


===Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit===
===Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit===


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{{ABSTRACT_PUBMED_17662946}}
{{ABSTRACT_PUBMED_17662946}}


==Disease==
==About this Structure==
Known disease associated with this structure: Gastrointestinal stromal tumor, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Germ cell tumors OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Leukemia, acute myeloid OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Mast cell leukemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Mastocytosis with associated hematologic disorder OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Piebaldism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]]
[[2ec8]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EC8 OCA].  


==About this Structure==
==See Also==
2EC8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EC8 OCA].
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17662946</ref><references group="xtra"/>
<ref group="xtra">PMID:017662946</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
Line 40: Line 28:
[[Category: Receptor tyrosine kinase]]
[[Category: Receptor tyrosine kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:06:19 2009''

Revision as of 10:22, 27 July 2012

File:2ec8.png

Template:STRUCTURE 2ec8

Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit

Template:ABSTRACT PUBMED 17662946

About this Structure

2ec8 is a 1 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Yuzawa S, Opatowsky Y, Zhang Z, Mandiyan V, Lax I, Schlessinger J. Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. Cell. 2007 Jul 27;130(2):323-34. PMID:17662946 doi:https://dx.doi.org/10.1016/j.cell.2007.05.055

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