3f5x: Difference between revisions

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{{Seed}}
[[Image:3f5x.png|left|200px]]
[[Image:3f5x.jpg|left|200px]]


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{{STRUCTURE_3f5x|  PDB=3f5x  |  SCENE=  }}  
{{STRUCTURE_3f5x|  PDB=3f5x  |  SCENE=  }}  


===CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site===
===CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site===


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{{ABSTRACT_PUBMED_19097791}}
{{ABSTRACT_PUBMED_19097791}}


==About this Structure==
==About this Structure==
3F5X is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F5X OCA].  
[[3f5x]] is a 4 chain structure of [[Cell Division Protein Kinase 2]] and [[Cyclin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F5X OCA].  
 
==See Also==
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]]
*[[Cyclin|Cyclin]]


==Reference==
==Reference==
<ref group="xtra">PMID:19097791</ref><references group="xtra"/>
<ref group="xtra">PMID:019097791</ref><references group="xtra"/>
[[Category: Cyclin-dependent kinase]]
[[Category: Cyclin-dependent kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 46: Line 38:
[[Category: Cell division]]
[[Category: Cell division]]
[[Category: Cyclin]]
[[Category: Cyclin]]
[[Category: Cytoplasm]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Kinase]]
[[Category: Kinase]]
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[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Pkc]]
[[Category: Pkc]]
[[Category: Polymorphism]]
[[Category: Protein kinase]]
[[Category: Protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transferase/cell cycle complex]]
[[Category: Transferase-cell cycle complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb  4 11:37:49 2009''

Revision as of 11:10, 27 July 2012

File:3f5x.png

Template:STRUCTURE 3f5x

CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site

Template:ABSTRACT PUBMED 19097791

About this Structure

3f5x is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Trujillo JI, Kiefer JR, Huang W, Thorarensen A, Xing L, Caspers NL, Day JE, Mathis KJ, Kretzmer KK, Reitz BA, Weinberg RA, Stegeman RA, Wrightstone A, Christine L, Compton R, Li X. 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor. Bioorg Med Chem Lett. 2009 Feb 1;19(3):908-11. Epub 2008 Dec 6. PMID:19097791 doi:10.1016/j.bmcl.2008.11.105

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