1u65: Difference between revisions

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[[Image:1u65.png|left|200px]]
[[Image:1u65.png|left|200px]]


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{{STRUCTURE_1u65|  PDB=1u65  |  SCENE=  }}  
{{STRUCTURE_1u65|  PDB=1u65  |  SCENE=  }}  


===Ache W. CPT-11===
===Ache W. CPT-11===


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{{ABSTRACT_PUBMED_15772291}}


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*[[AChE bivalent inhibitors (Part II)|AChE bivalent inhibitors (Part II)]]
*[[AChE bivalent inhibitors (Part II)|AChE bivalent inhibitors (Part II)]]
*[[Acetylcholinesterase|Acetylcholinesterase]]
*[[Acetylcholinesterase|Acetylcholinesterase]]
*[[Alzheimer's Disease|Alzheimer's Disease]]
*[[User:Boris Brumshtein|User:Boris Brumshtein]]
*[[User:Boris Brumshtein|User:Boris Brumshtein]]



Revision as of 11:19, 27 July 2012

File:1u65.png

Template:STRUCTURE 1u65

Ache W. CPT-11

Template:ABSTRACT PUBMED 15772291

About this Structure

1u65 is a 1 chain structure of Acetylcholinesterase with sequence from Torpedo californica. Full crystallographic information is available from OCA.

See Also

Reference

  1. Harel M, Hyatt JL, Brumshtein B, Morton CL, Yoon KJ, Wadkins RM, Silman I, Sussman JL, Potter PM. The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action. Mol Pharmacol. 2005 Jun;67(6):1874-81. Epub 2005 Mar 16. PMID:15772291 doi:https://dx.doi.org/10.1124/mol.104.009944

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