3s2a: Difference between revisions

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[[Image:3s2a.png|left|200px]]
[[Image:3s2a.png|left|200px]]


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{{STRUCTURE_3s2a|  PDB=3s2a  |  SCENE=  }}  
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===Crystal structure of PI3K-gamma in complex with a quinoline inhibitor===
===Crystal structure of PI3K-gamma in complex with a quinoline inhibitor===


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{{ABSTRACT_PUBMED_21612232}}
{{ABSTRACT_PUBMED_21612232}}


==About this Structure==
==About this Structure==
[[3s2a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2A OCA].  
[[3s2a]] is a 1 chain structure of [[Phosphoinositide 3-Kinases]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2A OCA].  
 
==See Also==
*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]


==Reference==
==Reference==

Revision as of 11:26, 27 July 2012

File:3s2a.png

Template:STRUCTURE 3s2a

Crystal structure of PI3K-gamma in complex with a quinoline inhibitor

Template:ABSTRACT PUBMED 21612232

About this Structure

3s2a is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Nishimura N, Siegmund A, Liu L, Yang K, Bryan MC, Andrews KL, Bo Y, Booker SK, Caenepeel S, Freeman DJ, Liao H, McCarter JD, Mullady EL, San Miguel T, Subramanian R, Tamayo N, Wang L, Whittington DA, Zalameda LP, Zhang N, Hughes PE, Norman MH. Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure-Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives. J Med Chem. 2011 May 25. PMID:21612232 doi:10.1021/jm200386s

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