2f4j: Difference between revisions

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{{Seed}}
[[Image:2f4j.png|left|200px]]
[[Image:2f4j.png|left|200px]]


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{{STRUCTURE_2f4j|  PDB=2f4j  |  SCENE=  }}  
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===Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680===
===Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680===


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{{ABSTRACT_PUBMED_16424036}}
{{ABSTRACT_PUBMED_16424036}}


==About this Structure==
==About this Structure==
2F4J is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F4J OCA].  
[[2f4j]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F4J OCA].  
 
==See Also==
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16424036</ref><references group="xtra"/>
<ref group="xtra">PMID:016424036</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Kinase inhibitor]]
[[Category: Kinase inhibitor]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:11:59 2009''

Revision as of 11:31, 27 July 2012

File:2f4j.png

Template:STRUCTURE 2f4j

Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680

Template:ABSTRACT PUBMED 16424036

About this Structure

2f4j is a 1 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Young MA, Shah NP, Chao LH, Seeliger M, Milanov ZV, Biggs WH 3rd, Treiber DK, Patel HK, Zarrinkar PP, Lockhart DJ, Sawyers CL, Kuriyan J. Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680. Cancer Res. 2006 Jan 15;66(2):1007-14. PMID:16424036 doi:https://dx.doi.org/66/2/1007

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