3n4l: Difference between revisions
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[[Image:3n4l.png|left|200px]] | |||
[[Image:3n4l. | |||
{{STRUCTURE_3n4l| PDB=3n4l | SCENE= }} | {{STRUCTURE_3n4l| PDB=3n4l | SCENE= }} | ||
===BACE-1 in complex with ELN380842=== | ===BACE-1 in complex with ELN380842=== | ||
{{ABSTRACT_PUBMED_20634069}} | {{ABSTRACT_PUBMED_20634069}} | ||
==About this Structure== | ==About this Structure== | ||
[[3n4l]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4L OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020634069</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Hydroxyethylamine]] | [[Category: Hydroxyethylamine]] | ||
Revision as of 11:35, 27 July 2012
BACE-1 in complex with ELN380842
Template:ABSTRACT PUBMED 20634069
About this Structure
3n4l is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Truong AP, Probst GD, Aquino J, Fang L, Brogley L, Sealy JM, Hom RK, Tucker JA, John V, Tung JS, Pleiss MA, Konradi AW, Sham HL, Dappen MS, Toth G, Yao N, Brecht E, Pan H, Artis DR, Ruslim L, Bova MP, Sinha S, Yednock TA, Zmolek W, Quinn KP, Sauer JM. Improving the permeability of the hydroxyethylamine BACE-1 inhibitors: structure-activity relationship of P2' substituents. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4789-94. Epub 2010 Jun 25. PMID:20634069 doi:10.1016/j.bmcl.2010.06.112
