3hbb: Difference between revisions

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[[Image:3hbb.png|left|200px]]
[[Image:3hbb.png|left|200px]]


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{{STRUCTURE_3hbb|  PDB=3hbb  |  SCENE=  }}  
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===Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate===
===Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate===


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{{ABSTRACT_PUBMED_19564691}}


Revision as of 11:36, 27 July 2012

File:3hbb.png

Template:STRUCTURE 3hbb

Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate

Template:ABSTRACT PUBMED 19564691

About this Structure

3hbb is a 4 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

See Also

Reference

  1. Senkovich O, Schormann N, Chattopadhyay D. Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate. Acta Crystallogr D Biol Crystallogr. 2009 Jul;65(Pt 7):704-16. Epub 2009, Jun 20. PMID:19564691 doi:10.1107/S090744490901230X

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