3jz2: Difference between revisions
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[[Image:3jz2.png|left|200px]] | [[Image:3jz2.png|left|200px]] | ||
{{STRUCTURE_3jz2| PDB=3jz2 | SCENE= }} | {{STRUCTURE_3jz2| PDB=3jz2 | SCENE= }} | ||
===Crystal structure of human thrombin mutant N143P in E* form=== | ===Crystal structure of human thrombin mutant N143P in E* form=== | ||
{{ABSTRACT_PUBMED_19846563}} | {{ABSTRACT_PUBMED_19846563}} | ||
==About this Structure== | ==About this Structure== | ||
[[3jz2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ2 OCA]. | [[3jz2]] is a 2 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ2 OCA]. | ||
==See Also== | |||
*[[Thrombin|Thrombin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019846563</ref><ref group="xtra">PMID:018250335</ref><ref group="xtra">PMID:015152000</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Acute phase]] | [[Category: Acute phase]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Kringle]] | [[Category: Kringle]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 11:49, 27 July 2012
Crystal structure of human thrombin mutant N143P in E* form
Template:ABSTRACT PUBMED 19846563
About this Structure
3jz2 is a 2 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Niu W, Chen Z, Bush-Pelc LA, Bah A, Gandhi PS, Di Cera E. Mutant N143P reveals how Na+ activates thrombin. J Biol Chem. 2009 Dec 25;284(52):36175-85. Epub 2009 Oct 21. PMID:19846563 doi:10.1074/jbc.M109.069500
- Gandhi PS, Chen Z, Mathews FS, Di Cera E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
- Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:https://dx.doi.org/10.1074/jbc.M401756200
