2fes: Difference between revisions
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[[Image:2fes.png|left|200px]] | [[Image:2fes.png|left|200px]] | ||
{{STRUCTURE_2fes| PDB=2fes | SCENE= }} | {{STRUCTURE_2fes| PDB=2fes | SCENE= }} | ||
===Orally active thrombin inhibitors=== | ===Orally active thrombin inhibitors=== | ||
{{ABSTRACT_PUBMED_16517159}} | {{ABSTRACT_PUBMED_16517159}} | ||
==About this Structure== | ==About this Structure== | ||
[[2fes]] is a 3 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FES OCA]. | |||
==See Also== | |||
*[[Thrombin|Thrombin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016517159</ref><references group="xtra"/> | ||
[[Category: Hirudo medicinalis]] | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Hoeffken, H W.]] | [[Category: Hoeffken, H W.]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Thrombin inhibitor]] | [[Category: Thrombin inhibitor]] | ||
Revision as of 12:56, 27 July 2012
Orally active thrombin inhibitors
Template:ABSTRACT PUBMED 16517159
About this Structure
2fes is a 3 chain structure of Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mack H, Baucke D, Hornberger W, Lange UE, Seitz W, Hoffken HW. Orally active thrombin inhibitors. Part 1: optimization of the P1-moiety. Bioorg Med Chem Lett. 2006 May 15;16(10):2641-7. Epub 2006 Mar 6. PMID:16517159 doi:10.1016/j.bmcl.2006.02.040