2x8d: Difference between revisions

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{{Seed}}
[[Image:2x8d.png|left|200px]]
[[Image:2x8d.png|left|200px]]


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===DISCOVERY OF A NOVEL CLASS OF TRIAZOLONES AS CHECKPOINT KINASE INHIBITORS - HIT TO LEAD EXPLORATION===
===DISCOVERY OF A NOVEL CLASS OF TRIAZOLONES AS CHECKPOINT KINASE INHIBITORS - HIT TO LEAD EXPLORATION===


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{{ABSTRACT_PUBMED_20673630}}


==About this Structure==
==About this Structure==
2X8D is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X8D OCA].  
[[2x8d]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X8D OCA].  
 
==See Also==
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20673630</ref><references group="xtra"/>
<ref group="xtra">PMID:020673630</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:25:24 2010''

Revision as of 13:35, 27 July 2012

File:2x8d.png

Template:STRUCTURE 2x8d

DISCOVERY OF A NOVEL CLASS OF TRIAZOLONES AS CHECKPOINT KINASE INHIBITORS - HIT TO LEAD EXPLORATION

Template:ABSTRACT PUBMED 20673630

About this Structure

2x8d is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Oza V, Ashwell S, Brassil P, Breed J, Deng C, Ezhuthachan J, Haye H, Horn C, Janetka J, Lyne P, Newcombe N, Otterbien L, Pass M, Read J, Roswell S, Su M, Toader D, Yu D, Yu Y, Valentine A, Webborn P, White A, Zabludoff S, Zheng X. Discovery of a novel class of triazolones as Checkpoint Kinase inhibitors--hit to lead exploration. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5133-8. Epub 2010 Jul 29. PMID:20673630 doi:10.1016/j.bmcl.2010.07.015

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