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[[Image:1ros.png|left|200px]]
[[Image:1ros.png|left|200px]]


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{{STRUCTURE_1ros|  PDB=1ros  |  SCENE=  }}  
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===Crystal structure of MMP-12 complexed to 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl-4-(4-ethoxy[1,1-biphenyl]-4-yl)-4-oxobutanoic acid===
===Crystal structure of MMP-12 complexed to 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl-4-(4-ethoxy[1,1-biphenyl]-4-yl)-4-oxobutanoic acid===


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{{ABSTRACT_PUBMED_15289103}}
{{ABSTRACT_PUBMED_15289103}}


==About this Structure==
==About this Structure==
[[1ros]] is a 2 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROS OCA].  
[[1ros]] is a 2 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROS OCA].  


==See Also==
==See Also==
*[[Elastase]]
*[[Elastase|Elastase]]
*[[Matrix metalloproteinase|Matrix metalloproteinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15289103</ref><references group="xtra"/>
<ref group="xtra">PMID:015289103</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Macrophage elastase]]
[[Category: Macrophage elastase]]

Revision as of 13:46, 27 July 2012

File:1ros.png

Template:STRUCTURE 1ros

Crystal structure of MMP-12 complexed to 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl-4-(4-ethoxy[1,1-biphenyl]-4-yl)-4-oxobutanoic acid

Template:ABSTRACT PUBMED 15289103

About this Structure

1ros is a 2 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Morales R, Perrier S, Florent JM, Beltra J, Dufour S, De Mendez I, Manceau P, Tertre A, Moreau F, Compere D, Dublanchet AC, O'Gara M. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76. PMID:15289103 doi:https://dx.doi.org/10.1016/j.jmb.2004.06.039

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