2qdj: Difference between revisions

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{{Seed}}
[[Image:2qdj.png|left|200px]]
[[Image:2qdj.png|left|200px]]


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{{STRUCTURE_2qdj|  PDB=2qdj  |  SCENE=  }}  
{{STRUCTURE_2qdj|  PDB=2qdj  |  SCENE=  }}  


===Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture===
===Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture===


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{{ABSTRACT_PUBMED_17996702}}
{{ABSTRACT_PUBMED_17996702}}


==Disease==
==About this Structure==
Known disease associated with this structure: Bladder cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Pinealoma with bilateral retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]]
[[2qdj]] is a 1 chain structure of [[Retinoblastoma protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDJ OCA].


==About this Structure==
==See Also==
2QDJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDJ OCA].
*[[Retinoblastoma protein|Retinoblastoma protein]]


==Reference==
==Reference==
<ref group="xtra">PMID:17996702</ref><references group="xtra"/>
<ref group="xtra">PMID:017996702</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hassler, M.]]
[[Category: Hassler, M.]]
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[[Category: Cyclin fold]]
[[Category: Cyclin fold]]
[[Category: Cyclin wedge]]
[[Category: Cyclin wedge]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:15:35 2009''

Revision as of 13:47, 27 July 2012

File:2qdj.png

Template:STRUCTURE 2qdj

Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture

Template:ABSTRACT PUBMED 17996702

About this Structure

2qdj is a 1 chain structure of Retinoblastoma protein with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Hassler M, Singh S, Yue WW, Luczynski M, Lakbir R, Sanchez-Sanchez F, Bader T, Pearl LH, Mittnacht S. Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. Mol Cell. 2007 Nov 9;28(3):371-85. PMID:17996702 doi:10.1016/j.molcel.2007.08.023

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