2f9b: Difference between revisions

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{{Seed}}
[[Image:2f9b.png|left|200px]]
[[Image:2f9b.png|left|200px]]


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{{STRUCTURE_2f9b|  PDB=2f9b  |  SCENE=  }}  
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===Discovery of Novel Heterocyclic Factor VIIa Inhibitors===
===Discovery of Novel Heterocyclic Factor VIIa Inhibitors===


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{{ABSTRACT_PUBMED_16460932}}


==Disease==
==About this Structure==
Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]]
[[2f9b]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F9B OCA].


==About this Structure==
==See Also==
2F9B is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F9B OCA].
*[[Factor VIIa|Factor VIIa]]


==Reference==
==Reference==
<ref group="xtra">PMID:16460932</ref><references group="xtra"/>
<ref group="xtra">PMID:016460932</ref><references group="xtra"/>
[[Category: Coagulation factor VIIa]]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 43: Line 31:
[[Category: Yu, C.]]
[[Category: Yu, C.]]
[[Category: Active site-directed inhibitor]]
[[Category: Active site-directed inhibitor]]
[[Category: Hydrolase-blood clotting complex]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Short hydrogen bond]]
[[Category: Short hydrogen bond]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:53:56 2009''

Revision as of 14:14, 27 July 2012

File:2f9b.png

Template:STRUCTURE 2f9b

Discovery of Novel Heterocyclic Factor VIIa Inhibitors

Template:ABSTRACT PUBMED 16460932

About this Structure

2f9b is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Rai R, Kolesnikov A, Sprengeler PA, Torkelson S, Ton T, Katz BA, Yu C, Hendrix J, Shrader WD, Stephens R, Cabuslay R, Sanford E, Young WB. Discovery of novel heterocyclic factor VIIa inhibitors. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2270-3. Epub 2006 Feb 3. PMID:16460932 doi:10.1016/j.bmcl.2006.01.017

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