2zm4: Difference between revisions

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{{Seed}}
[[Image:2zm4.png|left|200px]]
[[Image:2zm4.png|left|200px]]


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{{STRUCTURE_2zm4|  PDB=2zm4  |  SCENE=  }}  
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===Crystal structure of imidazo quinoxaline 1 bound to the kinase domain of human LCK, activated form (auto-phosphorylated on TYR394)===
===Crystal structure of imidazo quinoxaline 1 bound to the kinase domain of human LCK, activated form (auto-phosphorylated on TYR394)===


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{{ABSTRACT_PUBMED_18977146}}
{{ABSTRACT_PUBMED_18977146}}


==Disease==
==About this Structure==
Known disease associated with this structure: SCID due to LCK deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=153390 153390]]
[[2zm4]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] and [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZM4 OCA].


==About this Structure==
==See Also==
2ZM4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZM4 OCA].
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]
*[[Tyrosine kinase|Tyrosine kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18977146</ref><references group="xtra"/>
<ref group="xtra">PMID:018977146</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Tsuji, E.]]
[[Category: Tsuji, E.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Chromosomal rearrangement]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Host-virus interaction]]
[[Category: Host-virus interaction]]
Line 49: Line 35:
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:02:16 2009''
Retrieved from "https://proteopedia.org/2zm4"