2rbe: Difference between revisions
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[[Image:2rbe.png|left|200px]] | [[Image:2rbe.png|left|200px]] | ||
{{STRUCTURE_2rbe| PDB=2rbe | SCENE= }} | {{STRUCTURE_2rbe| PDB=2rbe | SCENE= }} | ||
===The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors=== | ===The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors=== | ||
{{ABSTRACT_PUBMED_17919905}} | {{ABSTRACT_PUBMED_17919905}} | ||
==About this Structure== | ==About this Structure== | ||
[[2rbe]] is a 4 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RBE OCA]. | |||
==See Also== | |||
*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017919905</ref><references group="xtra"/> | ||
[[Category: 11-beta-hydroxysteroid dehydrogenase]] | [[Category: 11-beta-hydroxysteroid dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Nadp]] | [[Category: Nadp]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Rossmann fold]] | [[Category: Rossmann fold]] | ||
[[Category: Signal-anchor]] | [[Category: Signal-anchor]] | ||
[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
Revision as of 14:27, 27 July 2012
The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors
Template:ABSTRACT PUBMED 17919905
About this Structure
2rbe is a 4 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yuan C, St Jean DJ Jr, Liu Q, Cai L, Li A, Han N, Moniz G, Askew B, Hungate RW, Johansson L, Tedenborg L, Pyring D, Williams M, Hale C, Chen M, Cupples R, Zhang J, Jordan S, Bartberger MD, Sun Y, Emery M, Wang M, Fotsch C. The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6056-61. Epub 2007 Sep 25. PMID:17919905 doi:10.1016/j.bmcl.2007.09.070
