3kqd: Difference between revisions

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{{Seed}}
[[Image:3kqd.png|left|200px]]
[[Image:3kqd.png|left|200px]]


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{{STRUCTURE_3kqd|  PDB=3kqd  |  SCENE=  }}  
{{STRUCTURE_3kqd|  PDB=3kqd  |  SCENE=  }}  


===Factor xa in complex with the inhibitor 1-(3-(5-oxo-4,5- dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'-(pyrrolidin-1- ylmethyl)biphenyl-4-yl)-3-(trifluoromethyl)-5,6-dihydro- 1h-pyrazolo[3,4-c]pyridin-7(4h)-one===
===Factor xa in complex with the inhibitor 1-(3-(5-oxo-4,5- dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'-(pyrrolidin-1- ylmethyl)biphenyl-4-yl)-3-(trifluoromethyl)-5,6-dihydro- 1h-pyrazolo[3,4-c]pyridin-7(4h)-one===


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{{ABSTRACT_PUBMED_20100660}}
{{ABSTRACT_PUBMED_20100660}}


==About this Structure==
==About this Structure==
3KQD is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KQD OCA].  
[[3kqd]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KQD OCA].  
 
==See Also==
*[[Factor Xa|Factor Xa]]


==Reference==
==Reference==
<ref group="xtra">PMID:20100660</ref><references group="xtra"/>
<ref group="xtra">PMID:020100660</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 29: Line 20:
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation factor]]
[[Category: Blood coagulation factor]]
[[Category: Calcium]]
[[Category: Calcium- binding]]
[[Category: Calcium- binding]]
[[Category: Egf-like domain]]
[[Category: Egf-like domain]]
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[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 11:21:45 2010''

Revision as of 14:44, 27 July 2012

File:3kqd.png

Template:STRUCTURE 3kqd

Factor xa in complex with the inhibitor 1-(3-(5-oxo-4,5- dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'-(pyrrolidin-1- ylmethyl)biphenyl-4-yl)-3-(trifluoromethyl)-5,6-dihydro- 1h-pyrazolo[3,4-c]pyridin-7(4h)-one

Template:ABSTRACT PUBMED 20100660

About this Structure

3kqd is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Quan ML, Pinto DJ, Rossi KA, Sheriff S, Alexander RS, Amparo E, Kish K, Knabb RM, Luettgen JM, Morin P, Smallwood A, Woerner FJ, Wexler RR. Phenyltriazolinones as potent factor Xa inhibitors. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1373-7. Epub 2010 Jan 11. PMID:20100660 doi:10.1016/j.bmcl.2010.01.011

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