2fnt: Difference between revisions
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[[Image:2fnt.png|left|200px]] | [[Image:2fnt.png|left|200px]] | ||
{{STRUCTURE_2fnt| PDB=2fnt | SCENE= }} | {{STRUCTURE_2fnt| PDB=2fnt | SCENE= }} | ||
===Crystal structure of a drug-resistant (V82A) inactive (D25N) HIV-1 protease complexed with AP2V variant of HIV-1 NC-p1 substrate.=== | ===Crystal structure of a drug-resistant (V82A) inactive (D25N) HIV-1 protease complexed with AP2V variant of HIV-1 NC-p1 substrate.=== | ||
{{ABSTRACT_PUBMED_16537628}} | {{ABSTRACT_PUBMED_16537628}} | ||
==About this Structure== | ==About this Structure== | ||
[[2fnt]] is a 3 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FNT OCA]. | |||
==See Also== | |||
*[[Virus protease|Virus protease]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016537628</ref><references group="xtra"/> | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
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[[Category: Flap conformation]] | [[Category: Flap conformation]] | ||
[[Category: Hiv-1 protease]] | [[Category: Hiv-1 protease]] | ||
[[Category: Hydrolase]] | |||
[[Category: Nc-p1 substrate]] | [[Category: Nc-p1 substrate]] | ||
[[Category: Structural intermediate]] | [[Category: Structural intermediate]] | ||
[[Category: Substrate recognition]] | [[Category: Substrate recognition]] | ||
Revision as of 14:47, 27 July 2012
Crystal structure of a drug-resistant (V82A) inactive (D25N) HIV-1 protease complexed with AP2V variant of HIV-1 NC-p1 substrate.
Template:ABSTRACT PUBMED 16537628
About this Structure
2fnt is a 3 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Prabu-Jeyabalan M, Nalivaika EA, Romano K, Schiffer CA. Mechanism of substrate recognition by drug-resistant human immunodeficiency virus type 1 protease variants revealed by a novel structural intermediate. J Virol. 2006 Apr;80(7):3607-16. PMID:16537628 doi:https://dx.doi.org/80/7/3607