1hky: Difference between revisions

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[[Image:1hky.gif|left|200px]]<br /><applet load="1hky" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1hky.gif|left|200px]]<br /><applet load="1hky" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1hky" />

'''SOLUTION STRUCTURE OF A PAN MODULE FROM EIMERIA TENELLA'''<br />

==Overview==

Micronemes, specialised organelles found in all apicomplexan parasites, secrete molecules that are essential for parasite attachment and invasion, of host cells. EtMIC5 is one such microneme protein that contains eleven, tandemly repeating modules. These modules have homology with the PAN, module superfamily. Members of this family are found in blood clotting, proteins, some growth factors and some nematode proteins. This paper, presents the structure of the 9th PAN module in EtMIC5, determined using, high resolution NMR. The structure shows similarities to and some, differences from the N-terminal module of hepatocyte growth factor (HGF), the only previous member of the PAN family with known structure.

Micronemes, specialised organelles found in all apicomplexan parasites, secrete molecules that are essential for parasite attachment and invasion of host cells. EtMIC5 is one such microneme protein that contains eleven tandemly repeating modules. These modules have homology with the PAN module superfamily. Members of this family are found in blood clotting proteins, some growth factors and some nematode proteins. This paper presents the structure of the 9th PAN module in EtMIC5, determined using high resolution NMR. The structure shows similarities to and some differences from the N-terminal module of hepatocyte growth factor (HGF), the only previous member of the PAN family with known structure.

==About this Structure==

1HKY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Eimeria_tenella Eimeria tenella]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1HKY OCA].

1HKY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Eimeria_tenella Eimeria tenella]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HKY OCA].

==Reference==

Line 13:

[[Category: Eimeria tenella]]

[[Category: Single protein]]

[[Category: Brown, P.J.]]

[[Category: Brown, P J.]]

[[Category: Campbell, I.D.]]

[[Category: Campbell, I D.]]

[[Category: Mulvey, D.]]

[[Category: Potts, J.R.]]

[[Category: Potts, J R.]]

[[Category: Tomley, F.M.]]

[[Category: Tomley, F M.]]

[[Category: eimeria tenella]]

[[Category: nmr]]

[[Category: pan module]]

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@@ Line 1: / Line 1: @@
-[[Image:1hky.gif|left|200px]]<br /><applet load="1hky" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1hky.gif|left|200px]]<br /><applet load="1hky" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1hky" />
 '''SOLUTION STRUCTURE OF A PAN MODULE FROM EIMERIA TENELLA'''<br />
 ==Overview==
-Micronemes, specialised organelles found in all apicomplexan parasites, secrete molecules that are essential for parasite attachment and invasion, of host cells. EtMIC5 is one such microneme protein that contains eleven, tandemly repeating modules. These modules have homology with the PAN, module superfamily. Members of this family are found in blood clotting, proteins, some growth factors and some nematode proteins. This paper, presents the structure of the 9th PAN module in EtMIC5, determined using, high resolution NMR. The structure shows similarities to and some, differences from the N-terminal module of hepatocyte growth factor (HGF), the only previous member of the PAN family with known structure.
+Micronemes, specialised organelles found in all apicomplexan parasites, secrete molecules that are essential for parasite attachment and invasion of host cells. EtMIC5 is one such microneme protein that contains eleven tandemly repeating modules. These modules have homology with the PAN module superfamily. Members of this family are found in blood clotting proteins, some growth factors and some nematode proteins. This paper presents the structure of the 9th PAN module in EtMIC5, determined using high resolution NMR. The structure shows similarities to and some differences from the N-terminal module of hepatocyte growth factor (HGF), the only previous member of the PAN family with known structure.
 ==About this Structure==
-HKY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Eimeria_tenella Eimeria tenella]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HKY OCA].
+HKY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Eimeria_tenella Eimeria tenella]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HKY OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Eimeria tenella]]
 [[Category: Single protein]]
-[[Category: Brown, P.J.]]
+[[Category: Brown, P J.]]
-[[Category: Campbell, I.D.]]
+[[Category: Campbell, I D.]]
 [[Category: Mulvey, D.]]
-[[Category: Potts, J.R.]]
+[[Category: Potts, J R.]]
-[[Category: Tomley, F.M.]]
+[[Category: Tomley, F M.]]
 [[Category: eimeria tenella]]
 [[Category: nmr]]
 [[Category: pan module]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 02:43:50 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:02:23 2008''