3bel: Difference between revisions

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[[Image:3bel.png|left|200px]]
[[Image:3bel.png|left|200px]]


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{{STRUCTURE_3bel|  PDB=3bel  |  SCENE=  }}  
{{STRUCTURE_3bel|  PDB=3bel  |  SCENE=  }}  


===X-ray structure of EGFR in complex with oxime inhibitor===
===X-ray structure of EGFR in complex with oxime inhibitor===


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{{ABSTRACT_PUBMED_18508264}}
{{ABSTRACT_PUBMED_18508264}}


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==See Also==
==See Also==
*[[Epidermal Growth Factor Receptor]]
*[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:18508264</ref><references group="xtra"/>
<ref group="xtra">PMID:018508264</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Struble, G T.]]
[[Category: Struble, G T.]]
[[Category: Xu, G.]]
[[Category: Xu, G.]]
[[Category: Alternative splicing]]
[[Category: Anti-oncogene]]
[[Category: Anti-oncogene]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Secreted]]
[[Category: Secreted]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Ubl conjugation]]

Revision as of 15:21, 27 July 2012

File:3bel.png

Template:STRUCTURE 3bel

X-ray structure of EGFR in complex with oxime inhibitor

Template:ABSTRACT PUBMED 18508264

About this Structure

3bel is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Xu G, Searle LL, Hughes TV, Beck AK, Connolly PJ, Abad MC, Neeper MP, Struble GT, Springer BA, Emanuel SL, Gruninger RH, Pandey N, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Greenberger LM. Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3495-9. Epub 2008 May 10. PMID:18508264 doi:https://dx.doi.org/10.1016/j.bmcl.2008.05.024

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