3en7: Difference between revisions

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{{Seed}}
[[Image:3en7.png|left|200px]]
[[Image:3en7.png|left|200px]]


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{{STRUCTURE_3en7|  PDB=3en7  |  SCENE=  }}  
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===Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor===
===Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor===


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{{ABSTRACT_PUBMED_18849971}}
{{ABSTRACT_PUBMED_18849971}}


==About this Structure==
==About this Structure==
3EN7 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EN7 OCA].  
[[3en7]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EN7 OCA].  
 
==See Also==
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18849971</ref><references group="xtra"/>
<ref group="xtra">PMID:018849971</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Knight, Z A.]]
[[Category: Knight, Z A.]]
[[Category: Shokat, K M.]]
[[Category: Shokat, K M.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
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[[Category: Tyrosine]]
[[Category: Tyrosine]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:08:58 2009''

Revision as of 15:22, 27 July 2012

File:3en7.png

Template:STRUCTURE 3en7

Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor

Template:ABSTRACT PUBMED 18849971

About this Structure

3en7 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. Epub 2008 Oct 12. PMID:18849971 doi:https://dx.doi.org/10.1038/nchembio.117

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