2c5y: Difference between revisions
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[[Image:2c5y.png|left|200px]] | [[Image:2c5y.png|left|200px]] | ||
{{STRUCTURE_2c5y| PDB=2c5y | SCENE= }} | {{STRUCTURE_2c5y| PDB=2c5y | SCENE= }} | ||
===DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN=== | ===DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN=== | ||
{{ABSTRACT_PUBMED_16492568}} | {{ABSTRACT_PUBMED_16492568}} | ||
==About this Structure== | ==About this Structure== | ||
[[2c5y]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] and [[Cyclin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5Y OCA]. | |||
==See Also== | |||
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] | |||
*[[Cyclin|Cyclin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016492568</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 15:50, 27 July 2012
DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN
Template:ABSTRACT PUBMED 16492568
About this Structure
2c5y is a 1 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM. Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design. Chem Biol. 2006 Feb;13(2):201-11. PMID:16492568 doi:https://dx.doi.org/10.1016/j.chembiol.2005.11.011
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Fischer, P M.
- Gibson, D.
- Kontopidis, G.
- Mcinnes, C.
- Mcnae, I.
- Mezna, M.
- Pandalaneni, S R.
- Thomas, M.
- Walkinshaw, M D.
- Wang, S.
- Wood, G.
- Atp-binding
- Cdk2
- Cell cycle
- Cell division
- Drug design
- Kinase
- Mitosis
- Nucleotide-binding
- Phosphorylation
- Serine/threonine-protein kinase
- Transferase
