3d4n: Difference between revisions

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{{Seed}}
[[Image:3d4n.png|left|200px]]
[[Image:3d4n.png|left|200px]]


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{{STRUCTURE_3d4n|  PDB=3d4n  |  SCENE=  }}  
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===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor===
===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor===


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{{ABSTRACT_PUBMED_18553955}}
{{ABSTRACT_PUBMED_18553955}}


==About this Structure==
==About this Structure==
3D4N is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4N OCA].  
[[3d4n]] is a 4 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4N OCA].  
 
==See Also==
*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18553955</ref><references group="xtra"/>
<ref group="xtra">PMID:018553955</ref><references group="xtra"/>
[[Category: 11-beta-hydroxysteroid dehydrogenase]]
[[Category: 11-beta-hydroxysteroid dehydrogenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Nadp]]
[[Category: Nadp]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Polymorphism]]
[[Category: Signal-anchor]]
[[Category: Signal-anchor]]
[[Category: Steroid metabolism]]
[[Category: Steroid metabolism]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:57:08 2009''

Revision as of 16:26, 27 July 2012

File:3d4n.png

Template:STRUCTURE 3d4n

Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor

Template:ABSTRACT PUBMED 18553955

About this Structure

3d4n is a 4 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Julian LD, Wang Z, Bostick T, Caille S, Choi R, Degraffenreid M, Di Y, He X, Hungate RW, Jaen JC, Liu J, Monshouwer M, McMinn D, Rew Y, Sudom A, Sun D, Tu H, Ursu S, Walker N, Yan X, Ye Q, Powers JP. Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model. J Med Chem. 2008 Jun 14;. PMID:18553955 doi:https://dx.doi.org/10.1021/jm800310g

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