1mf4: Difference between revisions

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[[Image:1mf4.png|left|200px]]
[[Image:1mf4.png|left|200px]]


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===Structure-based design of potent and selective inhibitors of phospholipase A2: Crystal structure of the complex formed between phosholipase A2 from Naja Naja sagittifera and a designed peptide inhibitor at 1.9 A resolution===
===Structure-based design of potent and selective inhibitors of phospholipase A2: Crystal structure of the complex formed between phosholipase A2 from Naja Naja sagittifera and a designed peptide inhibitor at 1.9 A resolution===


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{{ABSTRACT_PUBMED_14529280}}


==About this Structure==
==About this Structure==
1MF4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MF4 OCA].  
[[1mf4]] is a 2 chain structure of [[Phospholipase A2]] with sequence from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MF4 OCA].  
 
==See Also==
*[[Phospholipase A2|Phospholipase A2]]


==Reference==
==Reference==
<ref group="xtra">PMID:14529280</ref><references group="xtra"/>
<ref group="xtra">PMID:014529280</ref><references group="xtra"/>
[[Category: Naja sagittifera]]
[[Category: Naja sagittifera]]
[[Category: Dey, S.]]
[[Category: Dey, S.]]
Line 36: Line 27:
[[Category: Vikram, P.]]
[[Category: Vikram, P.]]
[[Category: Designed inhibitor]]
[[Category: Designed inhibitor]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Naja naja sagittifera]]
[[Category: Naja naja sagittifera]]
[[Category: Phospholipase a2]]
[[Category: Phospholipase a2]]
[[Category: Structure]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 10:05:03 2009''

Revision as of 16:39, 27 July 2012

File:1mf4.png

Template:STRUCTURE 1mf4

Structure-based design of potent and selective inhibitors of phospholipase A2: Crystal structure of the complex formed between phosholipase A2 from Naja Naja sagittifera and a designed peptide inhibitor at 1.9 A resolution

Template:ABSTRACT PUBMED 14529280

About this Structure

1mf4 is a 2 chain structure of Phospholipase A2 with sequence from Naja sagittifera. Full crystallographic information is available from OCA.

See Also

Reference

  1. Singh RK, Vikram P, Makker J, Jabeen T, Sharma S, Dey S, Kaur P, Srinivasan A, Singh TP. Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features. Biochemistry. 2003 Oct 14;42(40):11701-6. PMID:14529280 doi:10.1021/bi035076x

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