4em7: Difference between revisions
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[[Image:4em7.jpg|left|200px]] | |||
{{STRUCTURE_4em7| PDB=4em7 | SCENE= }} | |||
===Crystal structure of a topoisomerase ATP inhibitor=== | |||
{{ABSTRACT_PUBMED_22814212}} | |||
==About this Structure== | |||
[[4em7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_ga47373 Streptococcus pneumoniae ga47373]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EM7 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022814212</ref><references group="xtra"/> | |||
[[Category: Streptococcus pneumoniae ga47373]] | |||
[[Category: Boriack-Sjodin, P A.]] | |||
[[Category: Manchester, J.]] | |||
[[Category: Antimicrobial]] | |||
[[Category: Atp binding]] | |||
[[Category: Isomerase-isomerase inhibitor complex]] | |||
[[Category: Protein-inhibitor complex]] | |||
[[Category: Structure-based drug design]] | |||
[[Category: Virtual screen]] | |||
Revision as of 05:48, 1 August 2012
Crystal structure of a topoisomerase ATP inhibitor
Template:ABSTRACT PUBMED 22814212
About this Structure
4em7 is a 1 chain structure with sequence from Streptococcus pneumoniae ga47373. Full crystallographic information is available from OCA.
Reference
- Manchester JI, Dussault DD, Rose JA, Boriack-Sjodin PA, Uria-Nickelsen M, Ioannidis G, Bist S, Fleming P, Hull KG. Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5150-6. Epub 2012 Jun 19. PMID:22814212 doi:10.1016/j.bmcl.2012.05.128
