3tyv: Difference between revisions

Revision as of 10:24, 8 August 2012

3tyv is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Chen KX, Vibulbhan B, Yang W, Sannigrahi M, Velazquez F, Chan TY, Venkatraman S, Anilkumar GN, Zeng Q, Bennet F, Jiang Y, Lesburg CA, Duca J, Pinto P, Gavalas S, Huang Y, Wu W, Selyutin O, Agrawal S, Feld B, Huang HC, Li C, Cheng KC, Shih NY, Kozlowski JA, Rosenblum SB, Njoroge FG. Structure-Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase. J Med Chem. 2012 Jan 26;55(2):754-65. Epub 2012 Jan 6. PMID:22148957 doi:10.1021/jm201258k

@@ Line 1: / Line 1: @@
 [[Image:3tyv.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3tyv", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3tyv|  PDB=3tyv  |  SCENE=  }}
 ===SAR development and discovery of potent indole-based inhibitors of the hepatitis C virus NS5B polymerase===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_22148957}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 22148957 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_22148957}}