298d: Difference between revisions
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[[Image:298d.png|left|200px]] | [[Image:298d.png|left|200px]] | ||
{{STRUCTURE_298d| PDB=298d | SCENE= }} | {{STRUCTURE_298d| PDB=298d | SCENE= }} | ||
===TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2=== | ===TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2=== | ||
{{ABSTRACT_PUBMED_8917643}} | {{ABSTRACT_PUBMED_8917643}} | ||
==About this Structure== | ==About this Structure== | ||
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=298D OCA]. | [[298d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=298D OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:008917643</ref><ref group="xtra">PMID:018798655</ref><references group="xtra"/> | |||
[[Category: Blagburn, B L.]] | [[Category: Blagburn, B L.]] | ||
[[Category: Boykin, D W.]] | [[Category: Boykin, D W.]] | ||
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[[Category: B-dna]] | [[Category: B-dna]] | ||
[[Category: Complexed with drug]] | [[Category: Complexed with drug]] | ||
[[Category: Dna]] | |||
[[Category: Double helix]] | [[Category: Double helix]] | ||
Revision as of 16:43, 14 August 2012
TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2
Template:ABSTRACT PUBMED 8917643
About this Structure
298d is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Trent JO, Clark GR, Kumar A, Wilson WD, Boykin DW, Hall JE, Tidwell RR, Blagburn BL, Neidle S. Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2. J Med Chem. 1996 Nov 8;39(23):4554-62. PMID:8917643 doi:10.1021/jm9604484
- Nguyen B, Neidle S, Wilson WD. A role for water molecules in DNA-ligand minor groove recognition. Acc Chem Res. 2009 Jan 20;42(1):11-21. PMID:18798655 doi:10.1021/ar800016q
