StudioG24SecL04Tpc5: Difference between revisions
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==VlsE== | ==VlsE== | ||
<Structure load='1l8w' size='300' frame='true' align='right' caption='IR6:Immunodominate Region of VlsE' scene='StudioG24SecL04Tpc5/Ir6_highlight/3' /> | <Structure load='1l8w' size='300' frame='true' align='right' caption='IR6:Immunodominate Region of VlsE' scene='StudioG24SecL04Tpc5/Ir6_highlight/3' /> | ||
The causative agent of Lyme disease, a multi-stage infection, is a family of spirochetes found in the guts of Ixodes ticks. The Variable Major Protein (VMP)-like sequence Expressed (VlsE) is the specific outer-surface lipoprotein that enables the spirochete to evade immune response through mechanisms of antigenic variation. In addition to inducing a strong immune response in the host, VlsE is useful in the serodiagnosis of Lyme disease (Eicken et al.). | |||
==Structural Overview== | ==Structural Overview== | ||
