G09SecL04Tpc2: Difference between revisions
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The c-terminal is heavily involved in the antigen:antibody complex unlike the n-terminal. The c-terminal houses a protruding ridge of three loops: <scene name='G09SecL04Tpc2/3loops/1'>loop 1</scene> contains residues 203-220; <scene name='G09SecL04Tpc2/3loops/2'>loop 2</scene> contains residues 224-233; <scene name='G09SecL04Tpc2/3loops/3'>loop 3</scene> contains residues 246-257. These loops define the LA-2 (antibody) [http://en.wikipedia.org/wiki/Epitope epitope]. More specifically, the loops indicate where the antibody binds to the antigen. This protruding ridge coupled with OspA’s elongated fold gives the surface protein a high degree of mobility and surface exposure. | The c-terminal is heavily involved in the antigen:antibody complex unlike the n-terminal. The c-terminal houses a protruding ridge of three loops: <scene name='G09SecL04Tpc2/3loops/1'>loop 1</scene> contains residues 203-220; <scene name='G09SecL04Tpc2/3loops/2'>loop 2</scene> contains residues 224-233; <scene name='G09SecL04Tpc2/3loops/3'>loop 3</scene> contains residues 246-257. These loops define the LA-2 (antibody) [http://en.wikipedia.org/wiki/Epitope epitope]. More specifically, the loops indicate where the antibody binds to the antigen. This protruding ridge coupled with OspA’s elongated fold gives the surface protein a high degree of mobility and surface exposure. | ||
<scene name='G09SecL04Tpc2/3loops/4'>View All 3 Loops</scene> | |||
=== LA-2 Recognition === | === LA-2 Recognition === | ||
