G09SecL04Tpc2: Difference between revisions
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[[Image:Ospapic2.gif|thumb|right|Scanning electron micrograph of the spirochete ''Borrelia burgdorferi'', causative agent of Lyme disease.]] | [[Image:Ospapic2.gif|thumb|right|Scanning electron micrograph of the spirochete ''Borrelia burgdorferi'', causative agent of Lyme disease.]] | ||
'''Outer Surface Protein A (OspA)''' is a major [http://en.wikipedia.org/wiki/Lipoprotein lipoprotein] on the | '''Outer Surface Protein A (OspA)''' is a major [http://en.wikipedia.org/wiki/Lipoprotein lipoprotein] on the ''borrelia burgdorferi'' [http://en.wikipedia.org/wiki/Spirochete spirochete] which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions that are associated with [http://en.wikipedia.org/wiki/Lyme_Disease Lyme Disease] such as late stage neurological disorders including acute Lyme neuroborreliosis. | ||
== Introduction to Lyme Disease == | == Introduction to Lyme Disease == | ||
