G15SecL05Tpc3: Difference between revisions

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==Lyme Disease==

[http://www.cdc.gov/lyme/ Lyme disease] is a bacterial infectious disease of the skin, joints, nervous system and heart dominantly caused by the spirochete [http://en.wikipedia.org/wiki/Borrelia_burgdorferi.com ''Borrelia burgdorferi''], transmitted to humans via the bite of the deer tick [http://www.en.wikipedia.org/wiki/Tick ''Ixodes scapularis''] (Becker et al, 2005). The importance of antibodies in controlling such spirochaetal infections was underscored by the discovery of two particular antibodies with distinctive bactericidal properties: the monoclonal antibodies CB2 and H6831 (Connoly et al, 2005). When directed against the C-terminus of the outer-surface protein Osp-B, these fragments are bactericidal even in the absence of complements or phagocytes (Sadziene et al, 1994).

[http://www.cdc.gov/lyme/ Lyme disease] is a bacterial infectious disease of the skin, joints, nervous system and heart dominantly caused by the spirochete [http://en.wikipedia.org/wiki/Borrelia_burgdorferi.com ''Borrelia burgdorferi''], transmitted to humans via the bite of the deer tick [http://www.en.wikipedia.org/wiki/Tick ''Ixodes scapularis''] (Becker et al, 2005). The importance of antibodies in controlling such spirochaetal infections was underscored by the discovery of two particular antibodies with distinctive bactericidal properties: the [http://www.en.wikipedia.org/wiki/Monoclonal_antibodies monoclonal antibodies] CB2 and H6831 (Connoly et al, 2005). When directed against the C-terminus of the outer-surface protein Osp-B, these fragments are bactericidal even in the absence of complements or phagocytes (Sadziene et al, 1994).

== Outer Surface Protein B (Osp-B) of the ''Borrelia burgdorferi'' Spirochete Bacterium Function ==

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 ==Lyme Disease==
-[http://www.cdc.gov/lyme/ Lyme disease] is a bacterial infectious disease of the skin, joints, nervous system and heart dominantly caused by the spirochete [http://en.wikipedia.org/wiki/Borrelia_burgdorferi.com ''Borrelia burgdorferi''],  transmitted to humans via the bite of the deer tick [http://www.en.wikipedia.org/wiki/Tick ''Ixodes scapularis''] (Becker et al, 2005). The importance of antibodies in controlling such spirochaetal infections was underscored by the discovery of two particular antibodies with distinctive bactericidal properties: the monoclonal antibodies CB2 and H6831 (Connoly et al, 2005). When directed against the C-terminus of the outer-surface protein Osp-B, these fragments are bactericidal even in the absence of complements or phagocytes (Sadziene et al, 1994).
+[http://www.cdc.gov/lyme/ Lyme disease] is a bacterial infectious disease of the skin, joints, nervous system and heart dominantly caused by the spirochete [http://en.wikipedia.org/wiki/Borrelia_burgdorferi.com ''Borrelia burgdorferi''],  transmitted to humans via the bite of the deer tick [http://www.en.wikipedia.org/wiki/Tick ''Ixodes scapularis''] (Becker et al, 2005). The importance of antibodies in controlling such spirochaetal infections was underscored by the discovery of two particular antibodies with distinctive bactericidal properties: the [http://www.en.wikipedia.org/wiki/Monoclonal_antibodies monoclonal antibodies] CB2 and H6831 (Connoly et al, 2005). When directed against the C-terminus of the outer-surface protein Osp-B, these fragments are bactericidal even in the absence of complements or phagocytes (Sadziene et al, 1994).
 == Outer Surface Protein B (Osp-B) of the ''Borrelia burgdorferi'' Spirochete Bacterium Function ==