Introduction to Evolutionary Conservation: Difference between revisions
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Conserved surface patches identify functional regions of proteins. Less commonly, patches of high variability may also be functional. (Can you think of situations where high variability would be advantageous?<ref>Advantageous variability will be seen in these cases: [[5hmg]], [[2vaa]], [[3hi6]].</ref>) | Conserved surface patches identify functional regions of proteins. Less commonly, patches of high variability may also be functional. (Can you think of situations where high variability would be advantageous?<ref>Advantageous variability will be seen in these cases: [[5hmg]], [[2vaa]], [[3hi6]].</ref>) | ||
==Conservation in Proteopedia== | |||
Most molecules in Proteopedia, on pages titled with a [[PDB code]], have an ''Evolutionary Conservation'' line below the molecule. Clicking on <nowiki><b>[show]</b></nowiki> in this line will color the molecule by evolutionary conservation, as calculated by [[ConSurfDB_vs._ConSurf|ConSurfDB]]. | |||
==Conservation in FirstGlance== | |||
{{Clear}} | {{Clear}} | ||
